Pregabalin addiction and treatment

pregabalin addiction therapy

Get Help for Pregabalin Addiction

Our Clinical Team Specialise in Pregabalin Detox and Treatment
Kerry Canning, MBChB
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More on Pregabalin

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Pregabalin is prescribed to hundreds of thousands of people in the UK each year. For many, it provides relief from nerve pain, anxiety, and epilepsy.

What many don’t know is that pregabalin also carries a significant risk. This risk was serious enough that in 2019, the UK government reclassified it as a Class C controlled drug under the Misuse of Drugs Act. That decision wasn’t made lightly. It reflected growing evidence that pregabalin was being misused, that people were becoming dependent on it, and that in some cases the consequences were fatal.

If you’re taking pregabalin and something feels wrong, it may be time to seek help. Dependence can develop even when the medication is taken exactly as prescribed. It doesn’t mean you’ve done anything wrong. It means you may need support.

Talking to your GP is a reasonable first step. If you feel you need more specialist support, Castle Craig has been treating drug dependence since 1988. We’re here when you’re ready.

What is pregabalin?

Pregabalin is a prescription medication used to manage nerve pain, generalised anxiety disorder (GAD), and epilepsy. You may know it by its brand names: Lyrica, Alzain, or Axalid. It belongs to a class of medicines called gabapentinoids, which also includes gabapentin.

Doctors prescribe pregabalin in doses ranging from 50 mg to 600 mg daily, usually split across two or three doses. It’s available in several forms, including capsules and liquid.

In 2019, the UK government reclassified pregabalin as a Class C controlled substance. This followed growing evidence of misuse and deaths linked to the drug. According to the UK government, this reclassification introduced stricter rules: prescriptions must now be handwritten and signed by a doctor, dispensed within 28 days, and collected with proof of identity.

How pregabalin addiction develops

Pregabalin works by calming overactive nerve signals in the brain. Over time, your brain begins to rely on the drug to maintain that calm. That reliance is the beginning of dependence.

Dependence can develop even when you take pregabalin exactly as prescribed. That’s a known effect of how the drug works, not a reflection of the person taking it.

Pregabalin carries a risk of dependence for a wide range of people, not only those with a prior history of substance use.

If you have been taking pregabalin for some time and find that you need more of it to get the same effect, or that stopping it feels impossible, you may be experiencing dependence. That’s the starting point for getting help, not a reason to feel ashamed.

Signs of pregabalin addiction

Addiction to pregabalin can be hard to recognise, particularly when the drug was prescribed to you legitimately. The signs do not always look like what people imagine addiction to look like.

The DSM-5-TR is an American diagnostic tool. Clinicians use it to identify substance use disorder. DSM-5-TR stands for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision. Clinicians in the UK use it as a reference, but treatment here follows NHS pathways.

You may be experiencing pregabalin addiction (also known as Lyrica addiction) if you recognise some of the following in yourself. You’re taking higher doses than prescribed, or taking it for longer than intended. You’ve tried to cut down and found you can’t. Time starts to organise itself around pregabalin. When you last took it. When can you take it again? The parts of your life you valued start to suffer, often before you realise what is happening. You continue taking it even though you know it’s causing harm.

The presence of two or more of these suggests that dependence has developed. Two or three indicate mild dependence. Four or five indicates moderate dependence. Six or more indicates severe dependence.

Effects of pregabalin misuse

Pregabalin affects the central nervous system. When misused or taken in higher doses than prescribed, its effects on the brain and body become more pronounced.

While under the influence of higher doses, you may experience feelings of elation, increased energy, or a sense of detachment that feels calming. These are the effects that can make the drug feel rewarding, and that reinforce continued use.

Some people find themselves spending money they can’t afford, or making decisions they wouldn’t otherwise make.

According to the Office for National Statistics, pregabalin was mentioned in 617 drug poisoning deaths across England and Wales in 2024. Behind each figure is a person, and in many cases, a family who didn’t recognise the signs.

Risks of combining pregabalin with other substances

Pregabalin is a central nervous system (CNS) depressant. Taking it alongside other CNS depressant compounds can increase its effects, and that combination can be life-threatening.

Alcohol is a CNS depressant. So are opioids, benzodiazepines, and some other prescription medications. When you take pregabalin alongside any of these, your breathing can slow to a dangerous level.

Combining pregabalin with alcohol or other depressant medications is dangerous. If you’re using pregabalin alongside anything else, tell your doctor.

Pregabalin withdrawal symptoms

Stopping pregabalin suddenly isn’t safe. Your brain has adapted to the drug, and removing it suddenly can trigger a severe withdrawal reaction.

Pregabalin should always be reduced gradually and never stopped suddenly. In a residential setting, that process is monitored closely by medical staff who can respond if withdrawal symptoms become hard to manage.

Pregabalin withdrawal can cause physical symptoms. These include shaking, sweating, nausea, heart palpitations, dizziness, and headache. Anxiety, panic attacks, irritability, and difficulty sleeping are also common.

In more serious cases, withdrawal can cause seizures.

If you’re also using alcohol, heroin, or cannabis alongside pregabalin, withdrawal can be more challenging. Memory difficulties, intense anxiety, and panic can all be heightened when multiple substances are withdrawn together. This is why medically supervised withdrawal is recommended.

When to seek help

If you’re reading this, something has already made you stop and think about your pregabalin use. That’s worth taking seriously.

You don’t need to have reached a crisis point to deserve support. If you’re taking pregabalin without a prescription, or in doses higher than prescribed, that’s enough reason to speak to someone. If you were prescribed pregabalin and feel it’s taken hold in a way you didn’t expect, the team at Castle Craig can support your recovery.

A good starting point is your GP. They can assess your current use, talk through your options, and refer you to a specialist rehab service. If you’d prefer to speak to someone who specialises in pregabalin addiction, our team at Castle Craig is on hand to discuss your options.

For prescription drug addiction support, including pregabalin, you can find more information on our prescription drug addiction page.

Pregabalin addiction treatment at Castle Craig

Treatment for pregabalin addiction is different for every person. The right approach depends on your history with pregabalin and whether you are using other substances. Your medical history and health, wellbeing and normal environment also matter.

At Castle Craig, we offer residential treatment, supervised by our medical team, at our hospital in Scotland. Our clinical team carries out a full assessment before treatment begins. Your plan is built around what you need.

You’ve got 24-hour medical and nursing support throughout, so you won’t be managing this alone.

We treat pregabalin addiction alongside any co-occurring conditions, whether that is anxiety, chronic pain, depression, or trauma. Pregabalin often starts as a solution to something else: pain, anxiety, sleeplessness. We treat what was there before the addiction, not just the addiction itself.

Pregabalin detox and safe withdrawal

Medical detox is the first stage of residential treatment. For pregabalin, this means a carefully managed tapering process, not an abrupt stop.

Pregabalin should always be reduced gradually, never stopped suddenly. In a residential setting, that process is monitored closely by medical staff who can respond if withdrawal symptoms become difficult.

The length of pregabalin detox varies from person to person and will be determined by your clinical team.

For those withdrawing at home or through an outpatient service, the process is typically longer. How long it lasts will depend on how much you have been taking and for how long, as well as how frequently you will access support services.

If you have epilepsy or a seizure condition (for which pregabalin is often prescribed to manage), that is factored into your plan from the start at Castle Craig. Your medical team will monitor you closely throughout and adjust your care as needed.

Where needed, our medical team may prescribe additional medication to manage any specific withdrawal symptoms during the withdrawal. 

Therapy and long-term recovery

Getting through detox is one thing. Understanding what drove the dependency is another, and that’s what therapy is for.

At Castle Craig, rehab treatment includes our therapy programme. This consists of individual sessions with an addiction counsellor, group therapy, and specialist programmes for co-occurring conditions. Cognitive Behavioural Therapy (CBT) is a core part of our approach. It helps you identify the thoughts and situations that drove your use of pregabalin and develop practical responses to them.

If anxiety, pain, or sleep difficulties were the reason pregabalin was originally prescribed, we work with you on managing those without the drug. Recovery means finding ways to live well, not just removing the substance.

Our pregabalin rehab programme combines detox, therapy, and skills training in a structured residential setting. Our goal is to give you the tools to manage your recovery at home long-term.

Life after pregabalin treatment

Leaving treatment isn’t the end of the process. For most people, it’s closer to the beginning of a different phase.

At Castle Craig, we provide aftercare support following residential treatment. This includes continuing therapy and access to our alumni network. If things feel difficult after discharge, we are here.

The first few weeks at home can be disorienting. The routine of residential treatment is gone, and the world hasn’t stood still while you were away. That’s something we talk about before you leave, not after. Recovery at home looks different for everyone. Some days will feel manageable, others less so, and both are part of the same journey.

If you’ve been through treatment before, that experience counts for something. You know yourself better than you did the first time, and that matters.

Contact us

If you’re concerned about pregabalin addiction or you want to understand what treatment at Castle Craig involves, please call our team. We’re available to answer your questions, with no obligation and no pressure.

Frequently asked questions

  • Is pregabalin addictive?

    Pregabalin carries a genuine risk of dependence. This is why it was reclassified as a Class C controlled substance in the UK in 2019. The risk varies depending on the individual, but it isn’t limited to people with a prior history of substance use.

  • Can you become addicted to pregabalin if it has been prescribed to you?

    Yes. Dependence can develop when pregabalin is taken as prescribed, at the recommended dose, over a period of time. This is a known risk of the medication, not the result of misuse or recklessness. If you’re concerned about your relationship with a prescribed medication, your GP is the right first step

  • What are the withdrawal symptoms of pregabalin?

    Pregabalin withdrawal can cause physical symptoms, including shaking, sweating, nausea, heart palpitations, dizziness, and headache. Anxiety, panic attacks, irritability, and difficulty sleeping are also common. In serious cases, seizures can occur. The severity depends on how much you have been taking and for how long. Withdrawal should always be managed with medical support.

  • Can I stop taking pregabalin on my own?

    Stopping pregabalin suddenly isn’t safe. The dose needs to be reduced gradually, with appropriate medical supervision. Attempting to stop alone carries real risk. This is especially true if you’ve been taking it for a long time or in high doses. Please speak to your GP or contact our team before making any changes to how you’re taking pregabalin.

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